offpeak

AstraZeneca

Principal Product Engineer - Evinova

1 Medimmune Way, Gaithersburg, MD 20878

Full-time · $172k–$259k (as posted)

First seen by offpeak October 4, 2026

See your drive time Apply on AstraZeneca's site

The Role

We are looking for a pragmatic builder-architect — a senior engineer who ships fast without leaving a mess, and makes architectural choices that hold up as the product scales. This is a hands-on technical leadership role: roughly 40% writing code and prototyping, with the remainder spent on architecture, mentoring, and raising the engineering bar within your team.

You will embed with a product team for extended periods, owning technical direction and building AI-powered features end-to-end — from idea through production. You won’t just advise; you’ll build, and what you build will set the pattern for others. You may end up managing some engineers.

Most engineers lean one way. “Hackers” ship fast but accrue debt; “architects” build clean abstractions but stall on delivery. You are both. You know when to prototype loosely and when to invest in the durable version — and you can articulate why.

What You’ll Do

What We’re Looking For

Engineering Judgment

AI Engineering

Working with Teams

Learning

Technical Environment

Our stack spans the following. We don’t expect mastery of all of it — but given the role, you should be able to pick up almost any of it quickly.

Requirements

Nice to Have

When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $172,466.00 - $258,700.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Are you ready to bring new insights and fresh thinking to the table? Fantastic! We have one seat available, and we hope it’s yours. Apply today.

Date Posted

14-Oct-2026

Closing Date

26-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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