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Trustees of University of Pennsylvania

Research Specialist A

3400 Spruce Street, Philadelphia, PA 19104

Full-time · $45k–$51k (as posted)

First seen by offpeak October 21, 2026

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University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Research Specialist A

Job Profile Title

Research Specialist A

Job Description Summary

We are seeking a highly motivated and skilled Research Technician to join our laboratory at the Center for Neurodegenerative Disease Research (CNDR). The successful candidate will contribute to cutting-edge research investigating the role of TDP-43 protein aggregation in glial cells and its involvement in Frontotemporal Lobar Degeneration (FTLD-TDP), Amyotrophic Lateral Sclerosis (ALS), and related neurodegenerative disorders. This is an exciting opportunity to work in a collaborative research environment and gain experience with advanced cellular and molecular approaches used to study disease mechanisms.

Key responsibilities: The successful candidate will conduct research on neurodegenerative diseases using primary rodent and iPSC-derived cellular models, applying a range of cell biology, molecular biology, and imaging techniques. Responsibilities include designing and performing experiments, analyzing and interpreting data, maintaining cell cultures and accurate research records, and contributing to publications, presentations, and collaborative scientific activities within the laboratory at the Center of Neurodegenerative Disease Research (CNDR).

Job Description

Job Responsibilities

The successful candidate will contribute to research on neurodegenerative diseases using both established and innovative experimental approaches. The candidate will independently perform experiments using primary rat and mouse oligodendrocyte cultures, as well as induced pluripotent stem cell (iPSC)-derived neuronal and glial models. Responsibilities include conducting a variety of in vitro assays, such as transfection, transduction, biochemical analyses, and immunocytochemistry.

The candidate will also perform cell culture-related activities, including the establishment of non-neuronal cell lines, cryopreservation, thawing, and routine cell propagation, as needed. Additional responsibilities include analyzing experimental data, contributing to data interpretation, and collaborating with research team members to design and execute experiments.

The successful candidate will maintain accurate and detailed records of experimental procedures and results, assist in the preparation of research reports, and contribute to scientific manuscripts and presentations as appropriate. Participation in laboratory meetings, scientific discussions, and Center activities is expected. The candidate will also be required to attend and present research findings at laboratory meetings and other Center-related events.

Qualifications

Position contingent upon funding

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$45,278.00 - $51,000.00 Annual Rate

Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered.

Equal Opportunity Statement 

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

Special Requirements 
Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits

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To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay 

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