offpeak

AstraZeneca

Director, Portfolio, Resourcing and Transformation

35 Gatehouse Dr, Waltham, MA 02451

Full-time · $159k–$239k (as posted)

First seen by offpeak October 10, 2026

See your drive time Apply on AstraZeneca's site


About the role



At AstraZeneca, we’re not afraid to do things differently. We’re building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening up new ways to work, pioneering ground-breaking methods and bringing cross-functional teams together.

Biologics Engineering (BE) and Oncology Targeted Discovery (OTD) are pivotal organizations of over 1,000 people building the AstraZeneca portfolio across Biopharmaceuticals, Oncology and Infectious Diseases. With our ambition of delivering 20 new medicines by 2030, we must decide clearly where to invest our scientific capacity, bring AI into how we discover and develop medicines, and build next-generation talent.



This role sits where science, portfolio and transformation meet. You will shape how our scientific capacity is allocated across therapy areas, and how we decide what to start, continue, slow or stop. And you will lead strategic and transformation projects, including bringing AI into how we work, with direct exposure to senior scientific and functional leadership.



The ideal candidate combines analytical difficulty with the standing to align senior leaders who do not report to them. They are as comfortable facilitating a decision between Vice Presidents as they are building the numbers that make that decision possible, and they hold both to the same standard.



You will be responsible for



1. Portolio resource allocation and decision-making.




2. Strategic projects and transformation




3. Leadership and organizational effectiveness



Essential qualifications and experience




Desirable



The annual base pay for this position ranges from $159,180.80 - $238,771.20. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.


When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Date Posted

12-Oct-2026

Closing Date

11-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

More jobs within a 30-minute drive of Cambridge, MA