Manager, Research and Development – Integrated Genomics Operation

About Us:

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.

Exciting Opportunity at MSK: The Integrated Genomics Operation (IGO) at MSK is seeking a Manager, Research and Development to lead the evaluation, development, and implementation of cutting-edge genomics technologies. IGO is a high‑throughput core facility that enables basic, clinical, and translational cancer research by providing world‑class genomic services and expertise to MSK investigators. The team generates more than 100TB of data annually across 40+ genomic applications, including next‑generation approaches such as single‑cell and spatial transcriptomics.  

This is an outstanding opportunity for an experienced molecular biologist to combine scientific innovation, people leadership, and operational excellence in support of MSK’s mission to cure cancer. 

Role Overview:  

As the Manager, Research and Development, you will lead IGO’s R&D group and play a critical role in bringing novel genomic assays from concept to scalable, high‑throughput production.  

• Leading and supervising a team of technicians focused on testing and developing new genomics technologies.  

• Designing, evaluating, and optimizing novel assays, including feasibility assessments and protocol development.

• Maintaining detailed experimental records, technical documentation, and written summaries of research activities. 

• Identifying anomalies in experimental data and resolving root causes through systematic troubleshooting.  

• Partnering closely with IGO production teams to transition validated assays into efficient, sustainable, high‑throughput services. 

• Collaborating with internal and external stakeholders, including data analysts and scientific partners. 

• Mentoring team members, evaluating performance, and providing timely, constructive feedback.  

• Communicating scientific concepts clearly and effectively in lab meetings, cross‑functional forums, and institutional seminars.  

• Contributing creatively to problem‑solving while maintaining an appreciation for the operational and business aspects of a core facility. 

Key Qualifications:  

• PhD in Molecular Biology, Biochemistry, or a related discipline  

• Minimum of 3 years of postdoctoral experience in an academic research environment  

• Hands‑on experience with experimental and computational genomics methodologies  

• Strong publication record in NGS assay development  

• Excellent written, verbal, and interpersonal communication skills  

Core Skills:  

• Advanced expertise in molecular biology and genomics technologies.

• Strong analytical and problem‑solving abilities with exceptional attention to detail.  

• Ability to prioritize and adapt quickly in a dynamic environment.  

• Proven people‑leadership and mentorship capabilities.

• Collaborative mindset with the ability to build strong cross‑functional relationships.  

• Clear, adaptable communication style for diverse scientific and non‑scientific audiences.

• Consistent delivery of high‑quality results, even under ambitious circumstances.

Additional Information:  

• Schedule: On-Site, Monday – Friday, 37.5 hrs.  

• Location: 1250 First Avenue, New York, NY (Schwartz)  

• Reporting to: Integrated Genomics Operation (IGO) Leadership  

Helpful Links:  

• Compensation Philosophy 

• Benefits 

Closing:

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.  

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